Animal Models in Cancer Drug Discovery

Animal Models in Cancer Drug Discovery covers recent developments in tumor model systems for translational cancer research. Virtually all types of existing and emerging tumor models in use by the research community are discussed. Areas covered include the latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. Chapters on larger animal models, canine models and their use in pre-IND development make this a unique volume. In addition, sections on breeding methodologies and handling and assessment procedures make this book a must read.

This book will be a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations and knowledge seekers at all levels of the biomedical field.

• Encompasses discussions on innovative animal models, xenograft, genetic models, primary models, organoid system, humanized and other models in modern biology paradigms
• Covers the use of these models in personalized medicine, immunotherapy, toxicology, Pre-IN assessments and related drug development arenas
• Presents protocols, procedures and a comprehensive glossary to help newer readers understand technical terms and specialized nomenclature